Don Flott has 30 years of experience in administrative leadership roles at Mayo Clinic. During the past several years, he has focused on the value of laboratory diagnostics and its impact on a patient’s total cost of care. Flott—together with pathologists, scientists and clinicians—has developed data-driven methodologies for producing validated diagnostic clinical evidence that can drive out waste and impact the total cost of care for both hospitalized patients and those treated outside of the hospital setting.